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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG1 All Species: 13.07
Human Site: Y919 Identified Species: 26.14
UniProt: P18858 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18858 NP_000225.1 919 101736 Y919 G S D P E D T Y _ _ _ _ _ _ _
Chimpanzee Pan troglodytes XP_524321 919 101662 Y919 G S D P E D T Y _ _ _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001111346 919 101454 Y919 G S D P E D T Y _ _ _ _ _ _ _
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P37913 916 102271
Rat Rattus norvegicus Q9JHY8 918 102463
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P51892 1070 120215
Zebra Danio Brachydanio rerio NP_001119860 1058 118776 Y1058 K P D L E D Y Y _ _ _ _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1H4 747 84700
Honey Bee Apis mellifera XP_392286 861 97795 F860 T K I T E E D F Y _ _ _ _ _ _
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180844 967 108403 Y967 S K S E E D F Y _ _ _ _ _ _ _
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42572 790 87722
Baker's Yeast Sacchar. cerevisiae P04819 755 84810
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 98.2 N.A. N.A. 84 81.3 N.A. N.A. N.A. 56.9 56.1 N.A. 44 46 N.A. 48.5
Protein Similarity: 100 99.4 98.8 N.A. N.A. 89.3 87.8 N.A. N.A. N.A. 71.1 68.6 N.A. 60.2 65.7 N.A. 66.2
P-Site Identity: 100 100 100 N.A. N.A. 0 0 N.A. N.A. N.A. 0 50 N.A. 0 11.1 N.A. 37.5
P-Site Similarity: 100 100 100 N.A. N.A. 0 0 N.A. N.A. N.A. 0 50 N.A. 0 44.4 N.A. 37.5
Percent
Protein Identity: N.A. N.A. N.A. 40.3 36 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 34 0 0 42 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 50 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % F
% Gly: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 25 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 25 9 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 9 0 0 25 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 42 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 42 50 50 50 50 50 50 % _